| Josh | (11-5) | buf | atl | hou | chi | gb | phi | ne | cle | bal | lv | den | mia | sea | dal | kc | nyg | 47 |
| Mark N | (10-6) | buf | car | cin | chi | gb | phi | pit | tb | no | lv | jax | sf | sea | was | kc | nyg | 56 |
| John S | (9-7) | buf | atl | cin | chi | gb | phi | pit | tb | no | lv | jax | sf | sea | dal | kc | lar | 47 |
| Jeff | (9-7) | buf | car | hou | chi | gb | phi | pit | tb | no | lac | den | sf | sea | dal | kc | lar | 57 |
| Doug | (9-7) | buf | atl | hou | min | nyj | ten | pit | tb | no | lv | jax | sf | az | dal | kc | nyg | 44 |
| Bob | (9-7) | buf | atl | hou | chi | nyj | phi | pit | tb | bal | lac | jax | sf | az | was | kc | nyg | 48 |
| Todd | (9-7) | buf | car | cin | chi | gb | phi | pit | cle | bal | lv | den | sf | az | was | kc | nyg | 51 |
| John K | (7-9) | det | atl | cin | min | nyj | ten | pit | cle | no | lac | den | mia | az | was | ind | lar | 44 |
| Andy & Jeremy | (7-9) | det | car | hou | min | gb | phi | pit | tb | no | lac | jax | sf | sea | was | kc | nyg | 44 |
| Chris | (7-9) | det | car | cin | chi | gb | phi | ne | tb | no | lv | jax | mia | az | dal | kc | nyg | 49 |
| Jarrod | (7-9) | buf | car | hou | chi | nyj | ten | pit | tb | no | lv | jax | sf | sea | was | kc | nyg | 47 |
| Dylan | (6-10) | buf | atl | hou | min | nyj | phi | pit | tb | no | lv | den | mia | sea | was | ind | nyg | 50 |
| Mickey | (6-10) | buf | car | hou | min | gb | phi | ne | cle | no | lv | den | mia | az | dal | ind | lar | 42 |
| Mark L | (6-10) | buf | atl | cin | min | nyj | phi | pit | tb | bal | lac | den | sf | sea | dal | kc | nyg | 42 |
| Matthew | (6-10) | buf | car | hou | chi | gb | phi | pit | tb | bal | lv | jax | sf | sea | dal | kc | nyg | 40 |
| Mike | (5-11) | buf | car | cin | chi | gb | phi | pit | tb | no | lv | jax | sf | az | was | kc | lar | 52 |
| Tim & Kate | (5-11) | det | car | cin | min | nyj | phi | pit | tb | bal | lv | jax | mia | sea | dal | kc | nyg | 45 |
| Ross | (5-11) | det | car | cin | chi | nyj | phi | ne | tb | no | lv | den | sf | sea | dal | ind | nyg | 52 |
| Tacomaroma | (4-12) | det | atl | hou | chi | gb | phi | pit | tb | no | lv | jax | sf | az | was | ind | nyg | 47 |
| Home team in CAPS -- open: none | ||
| FAVORITE | SPREAD | UNDERDOG |
| Thursday, September 17: | ||
| (1-0) BUFFALO | 4.5 | Detroit (1-0) |
| Sunday, September 20: | ||
| (0-1) Carolina | 1.5 | ATLANTA (0-1) |
| (0-1) HOUSTON | 3 | Cincinnati (1-0) |
| (1-0) CHICAGO | 5.5 | Minnesota (1-0) |
| (0-1) Green Bay | 3.5 | NY JETS (1-0) |
| (1-0) Philadelphia | 7 | TENNESSEE (0-1) |
| (0-1) NEW ENGLAND | 5.5 | Pittsburgh (1-0) |
| (0-1) TAMPA BAY | 8.5 | Cleveland (0-1) |
| (1-0) BALTIMORE | 8.5 | New Orleans (0-1) |
| (0-1) LA CHARGERS | 7 | Las Vegas (1-0) |
| (0-1) DENVER | 2.5 | Jacksonville (1-0) |
| (1-0) SAN FRANCISCO | 13.5 | Miami (0-1) |
| (1-0) Seattle | 4.5 | ARIZONA (1-0) |
| (0-1) DALLAS | 3.5 | Washington (0-1) |
| (1-0) KANSAS CITY | 6.5 | Indianapolis (0-1) |
| Monday, September 21 | ||
| (0-1) LA RAMS | 7 | NY Giants (1-0) |